In early-1970s Las Vegas, low-level mobster Sam "Ace" Rothstein gets tapped by his bosses to head the Tangiers Casino. At first, he's a great success in the job, but over the years, problems with his loose-cannon enforcer Nicky Santoro, his ex-hustler wife Ginger, her con-artist ex Lester Diamond and a handful of corrupt politicians put Sam in ever-increasing danger.
A tough police sergeant's mother comes to visit him, and promptly starts trying to fix up his life, much to his embarrassment. For his birthday she buys him a machine gun out of the back of a van, and begins to further interfere with his job and love life, eventually helping him with a case he's on.
A New Jersey trucker creates a hit TV show with help from his girlfriend in the ratings business.